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MATERIAL PROFILE / Individual substance

Hexamethylene diisocyanate

CAS: 822-06-0

Function: Individual chemical research reference

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Awaiting human verification

This material’s published information has not yet been verified by a human reviewer.

Human verification concerns the stated information and scope. It is separate from an EcoSafe score, certification or safety approval.

Overview

Clear, colorless to slightly yellow liquid with a sharp, pungent odor. Source-checked chemical identity with NIOSH physical-property and occupational-hazard context. Supplier grade, manufacturing origin and EcoSafe assessment require separate review.

Chemistry: Hexamethylene diisocyanate

Listed supplier: Supplier not selected · substance baseline

Chemical identity

Molecular formula
C8H12N2O2
Molecular weight
168.19 g/mol (identity reference)
IUPAC name
1,6-diisocyanatohexane
PubChem CID
13192

Chemical identity only; purity, grade and supplier composition require separate documentation.

Identity snapshot: 2026-11-02 UTC.

CAS identity reference ↗

Core data coverage: 81.3%

13 of 16 defined fields have sourced information. This is data coverage, not a safety score, EcoSafe assessment or human-verification mark.

CAS cross-check: CAS 822-06-0 appears on the NIOSH card and in the returned PubChem CID’s synonyms. The CAS checksum and molecular-weight consistency were screened; variable-form and ambiguous matches were held out.

NIOSH identity & property source ↗ · PubChem CID 13192 ↗

Source context, synonyms & remaining gaps

Synonyms: 1,6-Diisocyanatohexane · HEXAMETHYLENE DIISOCYANATE · 1,6-Hexamethylene diisocyanate · Hexane, 1,6-diisocyanato- · Hexane 1,6-diisocyanate · 1,6-Hexylene diisocyanate · Hexamethylene-1,6-diisocyanate · Isocyanic acid, hexamethylene ester

Physical description: Clear, colorless to slightly yellow liquid with a sharp, pungent odor.

Occupational hazard context: irritation eyes, skin, respiratory system; cough, dyspnea (breathing difficulty), bronchitis, wheezing, pulmonary edema, asthma; corneal damage, skin blisters

The hazard text above reproduces the NIOSH symptoms field; it is not a complete GHS classification, exposure assessment or current supplier SDS. Read the original card and applicable supplier documentation.

Missing core fields: Uses · Density · SDS/TDS

Grade-specific properties, verified manufacturing origin and EcoSafe assessments are tracked separately and are not established by this import.

Source snapshot accessed 2026-11-02. The access date is not the source’s publication or revision date.

How the 16-field coverage score works →

Technical properties

NIOSH substance reference · not a supplier-grade specification. Source wording and units are retained, including °F. A missing temperature, pressure or test method has not been assumed. Specific gravity is not mass density; solubility and water reactivity are distinct.

PropertyValueConditions / method
SolubilityLow (Reacts)
Substance reference
Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card.
Method not stated in extracted NIOSH field
Source ↗
Boiling point415°F
Substance reference
Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card.
Method not stated in extracted NIOSH field
Source ↗
Specific gravity(77°F): 1.04
Substance reference
Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card.
Method not stated in extracted NIOSH field
Source ↗
Flash point284°F
Substance reference
Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card.
Method not stated in extracted NIOSH field
Source ↗
Melting / softening behavior-89°F
Substance reference
Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card.
Method not stated in extracted NIOSH field
Source ↗

Documents & supplier information

Archived copies are dated references. Confirm the latest document for your supplier, grade and region.

Hexamethylene diisocyanate — NIOSH Pocket Guide

Technical reference · CDC / NIOSH
Source revision: see original card; accessed November 2, 2026 · US occupational reference

Non-branded substance reference, not an SDS or exact-grade TDS. Contains physical properties and occupational hazard context; current supplier documentation is still needed.

Supplier access / request ↗

An exact-grade regional SDS has not yet been archived for this material.

Supplier and range referencesOriginal supplier / material reference ↗

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Suppliers & makers

Confirm grade, composition, current availability and production location directly with the supplier.

No material-specific supplier match has been added yet.

Documents, origin & assessment

Supplier documents
See Documents & supplier information above for linked references and gaps.
Manufacturing origin
Not verified
EcoSafe assessment
Not assessed · no numerical points or certification

Identity data and category placement do not establish safety, suitability or environmental performance. Obtain current grade-specific documentation.

Industries & categories

Industrial Chemicals
Base Chemicals & Intermediates · Organic Intermediates

Sources

Original material source ↗

Library source check: November 2, 2026. Sources may require supplier access.