MATERIAL PROFILE / Individual substance
CAS: 680-31-9
Function: Individual chemical research reference
Compare this material →This material’s published information has not yet been verified by a human reviewer.
Human verification concerns the stated information and scope. It is separate from an EcoSafe score, certification or safety approval.Clear, colorless liquid with an aromatic or mild, amine-like odor. [Note: A solid below 43°F.] Source-checked chemical identity with NIOSH physical-property and occupational-hazard context. Supplier grade, manufacturing origin and EcoSafe assessment require separate review.
Chemistry: Hexamethyl phosphoramide
Listed supplier: Supplier not selected · substance baseline
Chemical identity only; purity, grade and supplier composition require separate documentation.
Identity snapshot: 2026-11-02 UTC.
CAS identity reference ↗13 of 16 defined fields have sourced information. This is data coverage, not a safety score, EcoSafe assessment or human-verification mark.
CAS cross-check: CAS 680-31-9 appears on the NIOSH card and in the returned PubChem CID’s synonyms. The CAS checksum and molecular-weight consistency were screened; variable-form and ambiguous matches were held out.
NIOSH identity & property source ↗ · PubChem CID 12679 ↗
Synonyms: HEXAMETHYLPHOSPHORAMIDE · HMPA · Hexamethylphosphoric triamide · Hexametapol · Hempa · HMPTA · Hexamethylphosphoric acid triamide · Phosphoric hexamethyltriamide
Physical description: Clear, colorless liquid with an aromatic or mild, amine-like odor. [Note: A solid below 43°F.]
Occupational hazard context: irritation eyes, skin, respiratory system; dyspnea (breathing difficulty); abdominal pain; [potential occupational carcinogen]
The hazard text above reproduces the NIOSH symptoms field; it is not a complete GHS classification, exposure assessment or current supplier SDS. Read the original card and applicable supplier documentation.
Missing core fields: Uses · Density · SDS/TDS
Grade-specific properties, verified manufacturing origin and EcoSafe assessments are tracked separately and are not established by this import.
Source snapshot accessed 2026-11-02. The access date is not the source’s publication or revision date.
NIOSH substance reference · not a supplier-grade specification. Source wording and units are retained, including °F. A missing temperature, pressure or test method has not been assumed. Specific gravity is not mass density; solubility and water reactivity are distinct.
| Property | Value | Conditions / method |
|---|---|---|
| Solubility | Miscible Substance reference | Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card. Method not stated in extracted NIOSH field Source ↗ |
| Boiling point | 451°F Substance reference | Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card. Method not stated in extracted NIOSH field Source ↗ |
| Specific gravity | 1.03 Substance reference | Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card. Method not stated in extracted NIOSH field Source ↗ |
| Flash point | 220°F Substance reference | Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card. Method not stated in extracted NIOSH field Source ↗ |
| Melting / softening behavior | 43°F Substance reference | Conditions retained in source value where stated; otherwise unspecified. Confirm form and conditions in the original card. Method not stated in extracted NIOSH field Source ↗ |
Archived copies are dated references. Confirm the latest document for your supplier, grade and region.
Technical reference · CDC / NIOSH
Source revision: see original card; accessed November 2, 2026 · US occupational reference
Non-branded substance reference, not an SDS or exact-grade TDS. Contains physical properties and occupational hazard context; current supplier documentation is still needed.
Supplier access / request ↗An exact-grade regional SDS has not yet been archived for public access on this site.
Confirm grade, composition, current availability and production location directly with the supplier.
No material-specific supplier match has been added yet.
Identity data and category placement do not establish safety, suitability or environmental performance. Obtain current grade-specific documentation.
Industrial Chemicals
Base Chemicals & Intermediates · Organic Intermediates
Library source check: November 2, 2026. Sources may require supplier access.